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The IOP‐lowering effects and mechanism of action of tafluprost in prostanoid receptor‐deficient mice

AIM: To clarify the intraocular pressure (IOP)‐lowering profile of tafluprost, a newly synthesised prostaglandin F(2α) analogue, in mice. METHODS: C57BL/6J, and EP1, EP2, EP3 and postaglandin F (FP) receptor‐deficient wild‐type (WT), EP1KO, EP2KO, EP3KO and FPKO, respectively mice were bred and accl...

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Main Authors: Ota, Takashi, Aihara, Makoto, Saeki, Tadashiro, Narumiya, Shuh, Araie, Makoto
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Group 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1954775/
https://ncbi.nlm.nih.gov/pubmed/17124244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bjo.2006.105585
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