Highly Sensitive Method for Genomewide Detection of Allelic Composition in Nonpaired, Primary Tumor Specimens by Use of Affymetrix Single-Nucleotide–Polymorphism Genotyping Microarrays

Loss of heterozygosity (LOH), either with or without accompanying copy-number loss, is a cardinal feature of cancer genomes that is tightly linked to cancer development. However, detection of LOH is frequently hampered by the presence of normal cell components within tumor specimens and the limitati...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Yamamoto, Go , Nannya, Yasuhito , Kato, Motohiro , Sanada, Masashi , Levine, Ross L. , Kawamata, Norihiko , Hangaishi, Akira , Kurokawa, Mineo , Chiba, Shigeru , Gilliland, D. Gary , Koeffler, H. Phillip , Ogawa, Seishi 
Format: Artigo
Langue:Inglês
Publié: American Society of Human Genetics 2007
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950910/
https://ncbi.nlm.nih.gov/pubmed/17564968
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires