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Cellular Immune Response to an Engineered Cell-Based Tumor Vaccine at the Vaccination Site

The engineered expression of the immune co-stimulatory molecules CD80 and CD137L on the surface of a neuroblastoma cell line converts this tumor into a cell-based cancer vaccine. The mechanism by which this vaccine activates the immune system was investigated by capturing and analyzing immune cells...

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Autori principali: Zhou, Qiang, Johnson, Bryon D., Orentas, Rimas J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1949498/
https://ncbi.nlm.nih.gov/pubmed/17543914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2007.04.004
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