Adenovirus‐mediated expression of BMP‐7 suppresses the development of liver fibrosis in rats

BACKGROUND: Liver cirrhosis, which is caused by the accumulation of extracellular matrix materials, is a serious clinical problem that can progress to hepatic failure. Transforming growth factor‐β (TGFβ) plays a pivotal role in extracellular matrix production, but bone morphogenetic protein (BMP)‐7,...

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Detalhes bibliográficos
Main Authors: Kinoshita, Kohji, Iimuro, Yuji, Otogawa, Kohji, Saika, Shizuya, Inagaki, Yutaka, Nakajima, Yuji, Kawada, Norifumi, Fujimoto, Jiro, Friedman, Scott L, Ikeda, Kazuo
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2007
Assuntos:
Liver Fibrosis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1942155/
https://ncbi.nlm.nih.gov/pubmed/17127702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2006.092460
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