Combination therapy targeting the tumor microenvironment is effective in a model of human ocular melanoma

BACKGROUND: Ocular melanoma is the leading intraocular malignancy. There is no effective treatment for metastatic ocular melanoma. We sought a treatment targeting the tumor microenvironment as well as the tumor cells. METHODS: Migration of HUVEC cells, the ability of HUVEC cells to form tubes, and p...

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Autori principali: Mangiameli, David P, Blansfield, Joseph A, Kachala, Stephan, Lorang, Dominique, Schafer, Peter H, Muller, George W, Stirling, David I, Libutti, Steven K
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2007
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Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1941722/
https://ncbi.nlm.nih.gov/pubmed/17640369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-5-38
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