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Minocycline inhibits caspase-independent and -dependent mitochondrial cell death pathways in models of Huntington's disease
Minocycline is broadly protective in neurologic disease models featuring cell death and is being evaluated in clinical trials. We previously demonstrated that minocycline-mediated protection against caspase-dependent cell death related to its ability to prevent mitochondrial cytochrome c release. Th...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC193587/ https://ncbi.nlm.nih.gov/pubmed/12930891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1832501100 |
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