A study of loss of heterozygosity at 70 loci in anaplastic astrocytoma and glioblastoma multiforme with implications for tumor evolution.

Cancers that arise from astrocytes in the adult CNS present as either anaplastic astrocytomas (AAs) or as more aggressive glioblastomas multiforme (GBMs). GBMs either form de novo or progress from AAs. We proposed to examine the molecular genetic relationship between these CNS tumors by conducting a...

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Hauptverfasser: Wooten, E. C., Fults, D., Duggirala, R., Williams, K., Kyritsis, A. P., Bondy, M. L., Levin, V. A., O'Connell, P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1999
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1920743/
https://ncbi.nlm.nih.gov/pubmed/11550311
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