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Conformational changes in the expression domain of the Escherichia coli thiM riboswitch

The thiM riboswitch contains an aptamer domain that adaptively binds the coenzyme thiamine pyrophosphate (TPP). The binding of TPP to the aptamer domain induces structural rearrangements that are relayed to a second domain, the so-called expression domain, thereby interfering with gene expression. T...

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Bibliographic Details
Main Authors: Rentmeister, Andrea, Mayer, Günter, Kuhn, Nicole, Famulok, Michael
Format: Artigo
Language:Inglês
Published: Oxford University Press 2007
Subjects:
RNA
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1920254/
https://ncbi.nlm.nih.gov/pubmed/17517779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm300
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