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Hybrid survival motor neuron genes in patients with autosomal recessive spinal muscular atrophy: new insights into molecular mechanisms responsible for the disease.
Spinal muscular atrophy (SMA) is a frequent autosomal recessive neurodegenerative disorder leading to weakness and atrophy of voluntary muscles. The survival motor-neuron gene (SMN), a strong candidate for SMA, is present in two highly homologous copies (telSMN and cenSMN) within the SMA region. Onl...
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Main Authors: | , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
1996
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1914839/ https://ncbi.nlm.nih.gov/pubmed/8900234 |
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