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Pimecrolimus inhibits up-regulation of OX40 and synthesis of inflammatory cytokines upon secondary T cell activation by allogeneic dendritic cells

Pimecrolimus is a new non-steroidal inhibitor of T cell and mast cell activation. In the present study, we compared the potency of pimecrolimus and cyclosporin A (CyA) to inhibit cytokine synthesis of alloantigen-primed T cells and the expression of CD134 (OX40), an inducible co-receptor molecule th...

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Autors principals: KALTHOFF, F S, CHUNG, J, STUETZ, A
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906497/
https://ncbi.nlm.nih.gov/pubmed/12296857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2002.01962.x
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