Lack of evidence of a specific role for C4A gene deficiency in determining disease susceptibility among C4-deficient patients with systemic lupus erythematosus (SLE)

The aim of the present study was to investigate the prevalence of C4 and C2 deficiencies and to characterize genomic alterations in C4 genes in a large cohort of 125 unselected patients with SLE. We determined the protein concentration and functional activity of C2 and C4, as well as the C4 phenotyp...

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Autors principals: Dragon-Durey, M -A, Rougier, N, Clauvel, J -P, Caillat-Zucman, S, Remy, P, Guillevin, L, Liote, F, Blouin, J, Ariey, F, Lambert, B U, Kazatchkine, M D, Weiss, L
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2001
Matèries:
Rheumatic Disease
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905972/
https://ncbi.nlm.nih.gov/pubmed/11168010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2001.01438.x
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