Pirfenidone induces intercellular adhesion molecule-1 (ICAM-1) down-regulation on cultured human synovial fibroblasts

Pirfenidone has been shown to modify some cytokine regulatory actions and inhibit fibroblast biochemical reactions resulting in inhibition of proliferation and collagen matrix synthesis by fibroblast. We have investigated the effect of pirfenidone on the expression of cell adhesion molecules. The sy...

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Bibliographic Details
Main Authors: Kaneko, M, Inoue, H, Nakazawa, R, Azuma, N, Suzuki, M, Yamauchi, S, Margolin, S B, Tsubota, K, Saito, I
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 1998
Subjects:
Immunopharmacology/Immunotherapy
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1905007/
https://ncbi.nlm.nih.gov/pubmed/9697986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1998.00618.x
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