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Measurement of deoxyribonuclease I (DNase) in the serum and urine of systemic lupus erythematosus (SLE)-prone NZB/NZW mice by a new radial enzyme diffusion assay

A new radial enzyme diffusion (RED) method for the measurement of DNase activity in serum and urine is described. The sensitivity of the assay is in the range of 15.6–500 ng/ml. The assay is based on the hydrolysis of double-stranded (ds) DNA (or nucleosomes) in agarose. The specificity of the react...

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Autors principals: MACANOVIC, M, LACHMANN, P J
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904653/
https://ncbi.nlm.nih.gov/pubmed/9158089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.1997.3571249.x
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