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Rational design of an estrogen receptor mutant with altered DNA-binding specificity

Although artificial C2-H2 zinc fingers can be designed to recognize specific DNA sequences, it remains unclear to which extent nuclear receptor C4 zinc fingers can be tailored to bind novel DNA elements. Steroid receptors bind as dimers to palindromic response elements differing in the two central b...

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書誌詳細
主要な著者: Nguyen, Denis, Bail, Martine, Pesant, Genevieve, Dupont, Virginie N., Rouault, Étienne, Deschênes, Julie, Rocha, Walter, Melançon, Geneviève, Steinberg, Sergey V., Mader, Sylvie
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904296/
https://ncbi.nlm.nih.gov/pubmed/17478511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm241
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