Rotavirus Infection of Infant and Young Adult Nonobese Diabetic Mice Involves Extraintestinal Spread and Delays Diabetes Onset

Rotaviruses have been implicated as a possible viral trigger for exacerbations in islet autoimmunity, suggesting they might modulate type 1 diabetes development. In this study, the ability of rotavirus strain RRV to infect the pancreas and affect insulitis and diabetes was examined in nonobese diabe...

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Bibliographic Details
Main Authors: Graham, Kate L., O'Donnell, Joanne A., Tan, Yan, Sanders, Natalie, Carrington, Emma M., Allison, Janette, Coulson, Barbara S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2007
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900081/
https://ncbi.nlm.nih.gov/pubmed/17428851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00205-07
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