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c-Rel plays a key role in deficient activation of B cells from a non–X-linked hyper-IgM patient
Our previous results demonstrated that B cells from a patient (pt1) with non–X-linked hyper-IgM syndrome (HIGM) possess an atypical CD23(lo) phenotype that is unaffected by CD40-mediated activation. To investigate the molecular mechanism underlying defective CD23 expression in pt1 B cells, we used l...
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Main Authors: | , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
The American Society of Hematology
2006
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895478/ https://ncbi.nlm.nih.gov/pubmed/16896156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-03-008839 |
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