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Indeterminacy of Reverse Engineering of Gene Regulatory Networks: The Curse of Gene Elasticity

BACKGROUND: Gene Regulatory Networks (GRNs) have become a major focus of interest in recent years. A number of reverse engineering approaches have been developed to help uncover the regulatory networks giving rise to the observed gene expression profiles. However, this is an overspecified problem du...

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Main Authors: Krishnan, Arun, Giuliani, Alessandro, Tomita, Masaru
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1894653/
https://ncbi.nlm.nih.gov/pubmed/17593963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000562
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