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Biochemical and anatomical redistribution of tau protein in Alzheimer's disease.

We have developed assays that distinguish tau protein incorporated into the core structure of the paired helical filament (PHF) from non-PHF tau protein in brain tissue, whether soluble or insoluble. The PHF content was 19-fold greater in Alzheimer's disease cases compared with cognitively inta...

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Sonraí Bibleagrafaíochta
Main Authors: Mukaetova-Ladinska, E. B., Harrington, C. R., Roth, M., Wischik, C. M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1993
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1887045/
https://ncbi.nlm.nih.gov/pubmed/8342603
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