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Pancreatic adenocarcinomas frequently show p53 gene mutations.

Thirty-four pancreatic adenocarcinomas were studied for the presence of p53 gene mutations by the single-strand conformation polymorphism method and by direct sequencing of PCR-amplified fragments. p53 protein expression was immunohistochemically evaluated using monoclonal PAb1801 and polyclonal CM1...

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Bibliographic Details
Main Authors: Scarpa, A., Capelli, P., Mukai, K., Zamboni, G., Oda, T., Iacono, C., Hirohashi, S.
Format: Artigo
Language:Inglês
Published: 1993
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1886920/
https://ncbi.nlm.nih.gov/pubmed/8494051
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