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Effect of Apolipoprotein E Allele ε4 on the Initial Phase of Amyloid β-Protein Accumulation in the Human Brain
Deposition of amyloid β-protein (Aβ), a hallmark of Alzheimer’s disease, occurs to some extent in the brains of most elderly individuals. We sought to learn when Aβ deposition begins and how deposition is affected by apolipoprotein E allele ε4, a strong risk factor for late-onset Alzheimer’s disease...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1885772/ https://ncbi.nlm.nih.gov/pubmed/11106581 |
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