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Exposing the core promoter is sufficient to activate transcription and alter coactivator requirement at RNR3

Chromatin is a formidable barrier to transcription. Nucleosome density is lowest over the regulatory regions of active genes, and many repressed genes have a tightly positioned nucleosome over their core promoter. However, it has not been shown that nucleosome positioning is sufficient for repressio...

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Bibliographic Details
Main Authors: Zhang, Hesheng, Reese, Joseph C.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885588/
https://ncbi.nlm.nih.gov/pubmed/17502614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701666104
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