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Differential effects of bryostatin 1 and 12-O-tetradecanoyl-phorbol-13-acetate on the regulation and activation of RasGRP1 in mouse epidermal keratinocytes

The antitumor agent Bryostatin 1 (Bryo) and the tumor promoting phorbol esters function as structural mimetics of the second lipid messenger diacylglycerol (DAG) by binding to the C1 domain of DAG receptors. However, Bryo and the phorbol esters often differ in their cellular actions. In mouse skin,...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Tuthill, Matthew C., Oki, Carolyn E., Lorenzo, Patricia S.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2006
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885540/
https://ncbi.nlm.nih.gov/pubmed/16546974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-05-0317
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