Neuronal and microglial involvement in beta-amyloid protein deposition in Alzheimer's disease.

This study was undertaken to localize amyloid precursor protein (APP) and to determine how APP might be released and proteolyzed to yield the beta-amyloid protein deposits found in senile plaques in the brains of Alzheimer's disease patients. We found that antibodies to recombinantly expressed...

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Bibliografiske detaljer
Main Authors: Cras, P., Kawai, M., Siedlak, S., Mulvihill, P., Gambetti, P., Lowery, D., Gonzalez-DeWhitt, P., Greenberg, B., Perry, G.
Format: Artigo
Sprog:Inglês
Udgivet: 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1877622/
https://ncbi.nlm.nih.gov/pubmed/2117395
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