Pharmacokinetics and safety of JTE-522, a novel selective cyclooxygenase-2 inhibitor, in healthy male volunteers

AIMS: The pharmacokinetics and safety profile of JTE-522, 4-(4-cyclohexyl-2 methyloxazol-5-yl)-2-fluorobenzensulphonamide, a novel selective cyclooxygenase-2 inhibitor were investigated in healthy male volunteers. METHODS: Initially, as a pilot study, five groups of two subjects were given oral dose...

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Hlavní autoři: Ikeda, Yasuhiko, Umemura, Kazuo, Kondo, Kazunao, Nakashima, Mitsuyoshi, Kobayashi, Takuo, Takahashi, Mitsuru
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2002
Témata:
Pharmacokinetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874460/
https://ncbi.nlm.nih.gov/pubmed/12445023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2002.01676.x
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