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Novel Recombinant Parapoxvirus Vectors Induce Protective Humoral and Cellular Immunity against Lethal Herpesvirus Challenge Infection in Mice
Orf virus (ORFV; Parapoxvirus ovis) was used to develop a novel vector system for the generation of effective and safe live vaccines. Based on the attenuated ORFV strain D1701-V, recombinants were produced that express the glycoproteins gC (D1701-VrVgC) or gD (D1701-VrVgD) of the alphaherpesvirus of...
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Main Authors: | , , , |
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Format: | Artigo |
Jezik: | Inglês |
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American Society for Microbiology
2003
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC187421/ https://ncbi.nlm.nih.gov/pubmed/12915547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.17.9312-9323.2003 |
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