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Novel Recombinant Parapoxvirus Vectors Induce Protective Humoral and Cellular Immunity against Lethal Herpesvirus Challenge Infection in Mice

Orf virus (ORFV; Parapoxvirus ovis) was used to develop a novel vector system for the generation of effective and safe live vaccines. Based on the attenuated ORFV strain D1701-V, recombinants were produced that express the glycoproteins gC (D1701-VrVgC) or gD (D1701-VrVgD) of the alphaherpesvirus of...

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Sonraí Bibleagrafaíochta
Main Authors: Fischer, Timo, Planz, Oliver, Stitz, Lothar, Rziha, Hanns-Joachim
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2003
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC187421/
https://ncbi.nlm.nih.gov/pubmed/12915547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.17.9312-9323.2003
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