hTERT Gene Amplification and Increased mRNA Expression in Central Nervous System Embryonal Tumors

High-level gains at 5p15, a chromosomal region including the human telomerase catalytic protein subunit (hTERT) gene, have been documented in several medulloblastomas. We therefore analyzed hTERT gene dosage in a group of medulloblastomas and other embryonal brain tumors using differential PCR. Ampl...

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Bibliographic Details
Main Authors: Fan, Xing, Wang, Yunyue, Kratz, John, Brat, Dan J., Robitaille, Yves, Moghrabi, Albert, Perlman, Elizabeth J., Dang, Chi V., Burger, Peter C., Eberhart, Charles G.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2003
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Short Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868122/
https://ncbi.nlm.nih.gov/pubmed/12759234
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