Expression of Cyclooxygenase 2 Is an Independent Prognostic Factor in Human Ovarian Carcinoma

Cyclooxygenase-2 (COX-2) is the rate-limiting enzyme in prostanoid biosynthesis and is involved in tumor progression. We investigated expression of COX-1 and COX-2 in cell lines and tumors from ovarian carcinomas. Expression of COX-2 mRNA and protein was detectable in three of five ovarian carcinoma...

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Autors principals: Denkert, Carsten, Köbel, Martin, Pest, Sören, Koch, Ines, Berger, Stefan, Schwabe, Michael, Siegert, Antje, Reles, Angela, Klosterhalfen, Bernd, Hauptmann, Steffen
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2002
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Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867167/
https://ncbi.nlm.nih.gov/pubmed/11891188
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