Transcriptional elongation of non-coding bxd RNAs promoted by the Trithorax TAC1 complex represses Ubx by a transcriptional interference mechanism

Much of the genome is transcribed into long non-coding RNAs (ncRNAs). Previous data suggested that bithoraxoid (bxd) ncRNAs of the Drosophila bithorax complex prevent silencing of Ultrabithorax (Ubx), and recruit activating proteins of the trithorax group to their maintenance elements. We found that...

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Bibliografiska uppgifter
Huvudupphovsmän: Petruk, Svetlana, Sedkov, Yurii, Riley, Kristen M., Hodgson, Jacob, Schweisguth, Francois, Hirose, Susumu, Jaynes, James B., Brock, Hugh W., Mazo, Alexander
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2006
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866366/
https://ncbi.nlm.nih.gov/pubmed/17174895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2006.10.039
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