Transcriptional elongation of non-coding bxd RNAs promoted by the Trithorax TAC1 complex represses Ubx by a transcriptional interference mechanism

Much of the genome is transcribed into long non-coding RNAs (ncRNAs). Previous data suggested that bithoraxoid (bxd) ncRNAs of the Drosophila bithorax complex prevent silencing of Ultrabithorax (Ubx), and recruit activating proteins of the trithorax group to their maintenance elements. We found that...

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Hlavní autoři: Petruk, Svetlana, Sedkov, Yurii, Riley, Kristen M., Hodgson, Jacob, Schweisguth, Francois, Hirose, Susumu, Jaynes, James B., Brock, Hugh W., Mazo, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866366/
https://ncbi.nlm.nih.gov/pubmed/17174895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2006.10.039
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