Lymphopenia in the BB Rat Model of Type 1 Diabetes is Due to a Mutation in a Novel Immune-Associated Nucleotide (Ian)-Related Gene

The BB (BioBreeding) rat is one of the best models of spontaneous autoimmune diabetes and is used to study non-MHC loci contributing to Type 1 diabetes. Type 1 diabetes in the diabetes-prone BB (BBDP) rat is polygenic, dependent upon mutations at several loci. Iddm1, on chromosome 4, is responsible...

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Detalhes bibliográficos
Main Authors: MacMurray, Armand J., Moralejo, Daniel H., Kwitek, Anne E., Rutledge, Elizabeth A., Van Yserloo, Brian, Gohlke, Paul, Speros, Sara J., Snyder, Ben, Schaefer, Jonathan, Bieg, Sabine, Jiang, Jianjie, Ettinger, Ruth A., Fuller, Jessica, Daniels, Terri L., Pettersson, Anna, Orlebeke, Kimberly, Birren, Bruce, Jacob, Howard J., Lander, Eric S., Lernmark, Åke
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2002
Assuntos:
Letter
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC186618/
https://ncbi.nlm.nih.gov/pubmed/12097339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.412702
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