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Preclinical Evaluation of Microneedle Technology for Intradermal Delivery of Influenza Vaccines

Recent clinical studies have suggested that, for certain strains of influenza virus, intradermal (i.d.) delivery may enable protective immune responses using a lower dose of vaccine than required by intramuscular (i.m.) injection. Here, we describe the first preclinical use of microneedle technology...

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Autors principals: Alarcon, Jason B., Hartley, Andrea Waterston, Harvey, Noel G., Mikszta, John A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865614/
https://ncbi.nlm.nih.gov/pubmed/17329444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00387-06
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