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Pathway redundancy and protein essentiality revealed in the Saccharomyces cerevisiae interaction networks

The biological interpretation of genetic interactions is a major challenge. Recently, Kelley and Ideker proposed a method to analyze together genetic and physical networks, which explains many of the known genetic interactions as linking different pathways in the physical network. Here, we extend th...

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Hlavní autoři: Ulitsky, Igor, Shamir, Ron
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865586/
https://ncbi.nlm.nih.gov/pubmed/17437029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb4100144
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