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Hypermethylation of RASSF1A in Human and Rhesus Placentas

The pseudomalignant nature of the placenta prompted us to search for tumor suppressor gene hypermethylation, a phenomenon widely reported in cancer, in the human placenta. Nine tumor suppressor genes were studied. Hypermethylation of the Ras association domain family 1 A (RASSF1A) gene was found in...

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Bibliographic Details
Main Authors: Chiu, Rossa W.K., Chim, Stephen S.C., Wong, Ivy H.N., Wong, Cesar S.C., Lee, Wing-Shan, To, Ka F., Tong, Joanna H.M., Yuen, Ryan K.C., Shum, Alisa S.W., Chan, John K.C., Chan, Lisa Y.S., Yuen, Jessie W.F., Tong, Yu K., Weier, Jingly F., Ferlatte, Christy, Leung, Tse N., Lau, Tze K., Lo, Kwok W., Lo, Y.M. Dennis
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1864885/
https://ncbi.nlm.nih.gov/pubmed/17322379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060641
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