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Transforming growth factor-beta receptor type 2 mutations and microsatellite instability in sporadic colorectal adenomas and carcinomas.

Frame-shift mutations in a run of 10 adenines (A10) of the transforming growth factor-beta receptor type 2 gene (TGF-beta RII) are commonly seen in inherited and sporadic colonic cancers that exhibit microsatellite instability. A10 mutations and instability also are commonly seen in hereditary nonpo...

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Библиографические подробности
Главные авторы: Samowitz, W. S., Slattery, M. L.
Формат: Artigo
Язык:Inglês
Опубликовано: 1997
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1857921/
https://ncbi.nlm.nih.gov/pubmed/9212728
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