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Inhibitory effect of a toxin okadaic acid, isolated from the black sponge on smooth muscle and platelets.

1. Effects of okadaic acid, a toxin isolated from marine sponges, on smooth muscle contraction and platelet activation were examined. 2. Contractions in rabbit aorta induced by high concentrations of K+ and noradrenaline were inhibited by 0.1-1 microM okadaic acid in a concentration-dependent manner...

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Bibliografiske detaljer
Main Authors: Karaki, H., Mitsui, M., Nagase, H., Ozaki, H., Shibata, S., Uemura, D.
Format: Artigo
Sprog:Inglês
Udgivet: 1989
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1854712/
https://ncbi.nlm.nih.gov/pubmed/2555015
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