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A novel human B cell subpopulation representing the initial germinal center population to express AID

We have identified a novel mature human B-cell subpopulation in the human tonsil that has characteristics of both naive B cells and germinal center B cells including the expression of activation-induced cytidine deaminase (AID), which is essential for the process of immunoglobulin somatic hypermutat...

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Detalhes bibliográficos
Main Authors: Kolar, Grant R., Mehta, Darshna, Pelayo, Rosana, Capra, J. Donald
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852199/
https://ncbi.nlm.nih.gov/pubmed/17132718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-07-037150
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