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Tissue Injury Regulates Serotonin 1D Receptor Expression: Implications for the Control of Migraine and Inflammatory Pain

The anti-migraine action of “triptan” drugs involves the activation of serotonin subtype 1D (5-HT(1D)) receptors expressed on “pain-responsive” trigeminal primary afferents. In the central terminals of these nociceptors, the receptor is concentrated on peptidergic dense core vesicles (DCVs) and is n...

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Bibliographic Details
Main Authors: Ahn, Andrew H., Basbaum, Allan I.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851888/
https://ncbi.nlm.nih.gov/pubmed/16899728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1989-06.2006
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