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Ott1(Rbm15) has pleiotropic roles in hematopoietic development

OTT1(RBM15) was originally described as a 5′ translocation partner of the MAL(MKL1) gene in t(1,22)(p13;q13) infant acute mega karyocytic leukemia. OTT1 has no established physiological function, but it shares homology with the spen/Mint/SHARP family of proteins defined by three amino-terminal RNA r...

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Autores principales: Raffel, Glen D., Mercher, Thomas, Shigematsu, Hirokazu, Williams, Ifor R., Cullen, Dana E., Akashi, Koichi, Bernard, Olivier A., Gilliland, D. Gary
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851606/
https://ncbi.nlm.nih.gov/pubmed/17376872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609041104
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