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Transformation of the Proteasome with Age-related Macular Degeneration

The proteasome mediates pathways associated with oxidative stress and inflammation, two pathogenic events correlated with age-related macular degeneration (AMD). In human donor eyes corresponding to four stages of AMD, we found the proteasomal chymotrypsin-like activity increased in neurosensory ret...

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Détails bibliographiques
Auteurs principaux: Ethen, Cheryl M., Hussong, Stacy A., Reilly, Cavan, Feng, Xiao, Olsen, Timothy W., Ferrington, Deborah A.
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850528/
https://ncbi.nlm.nih.gov/pubmed/17289037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.01.061
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