Reduced-folate carrier (RFC) is expressed in placenta and yolk sac, as well as in cells of the developing forebrain, hindbrain, neural tube, craniofacial region, eye, limb buds and heart

BACKGROUND: Folate is essential for cellular proliferation and tissue regeneration. As mammalian cells cannot synthesize folates de novo, tightly regulated cellular uptake processes have evolved to sustain sufficient levels of intracellular tetrahydrofolate cofactors to support biosynthesis of purin...

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Bibliografische gegevens
Hoofdauteurs: Maddox, Dennis M, Manlapat, Anna, Roon, Penny, Prasad, Puttur, Ganapathy, Vadivel, Smith, Sylvia B
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2003
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC184426/
https://ncbi.nlm.nih.gov/pubmed/12887734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-3-6
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