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Trichostatin A sensitises rheumatoid arthritis synovial fibroblasts for TRAIL‐induced apoptosis
BACKGROUND: Histone acetylation/deacetylation has a critical role in the regulation of transcription by altering the chromatin structure. OBJECTIVE: To analyse the effect of trichostatin A (TSA), a streptomyces metabolite which specifically inhibits mammalian histone deacetylases, on TRAIL‐induced a...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BMJ Group
2006
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1798225/ https://ncbi.nlm.nih.gov/pubmed/16284094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2005.044065 |
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