Ovarian dysgerminomas are characterised by frequent KIT mutations and abundant expression of pluripotency markers

BACKGROUND: Ovarian germ cell tumours (OGCTs) typically arise in young females and their pathogenesis remains poorly understood. We investigated the origin of malignant OGCTs and underlying molecular events in the development of the various histological subtypes of this neoplasia. RESULTS: We examin...

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Autors principals: Hoei-Hansen, Christina E, Kraggerud, Sigrid M, Abeler, Vera M, Kærn, Janne, Rajpert-De Meyts, Ewa, Lothe, Ragnhild A
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2007
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797189/
https://ncbi.nlm.nih.gov/pubmed/17274819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-6-12
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