Genotype × Adiposity Interaction Linkage Analyses Reveal a Locus on Chromosome 1 for Lipoprotein-Associated Phospholipase A(2), a Marker of Inflammation and Oxidative Stress

Because obesity leads to a state of chronic, low-grade inflammation and oxidative stress, we hypothesized that the contribution of genes to variation in a biomarker of these two processes may be influenced by the degree of adiposity. We tested this hypothesis using samples from the San Antonio Famil...

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Main Authors: Diego, Vincent P., Rainwater, David L., Wang, Xing-Li, Cole, Shelley A., Curran, Joanne E., Johnson, Matthew P., Jowett, Jeremy B. M., Dyer, Thomas D., Williams, Jeff T., Moses, Eric K., Comuzzie, Anthony G., MacCluer, Jean W., Mahaney, Michael C., Blangero, John
Format: Artigo
Language:Inglês
Published: The American Society of Human Genetics 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1785310/
https://ncbi.nlm.nih.gov/pubmed/17160904
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