Cdk phosphorylation of the Ste11 transcription factor constrains differentiation-specific transcription to G(1)

Eukaryotic cells normally differentiate from G(1); here we investigate the mechanism preventing expression of differentiation-specific genes outside G(1). In fission yeast, induction of the transcription factor Ste11 triggers sexual differentiation. We find that Ste11 is only active in G(1) when Cdk...

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Bibliographic Details
Main Authors: Kjærulff, Søren, Andersen, Nicoline Resen, Borup, Mia Trolle, Nielsen, Olaf
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2007
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1785116/
https://ncbi.nlm.nih.gov/pubmed/17289922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.407107
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