Genetic evidence implicating DARPP-32 in human frontostriatal structure, function, and cognition

Dopamine- and cAMP-regulated phosphoprotein of molecular weight 32 kDa (DARPP-32), encoded by PPP1R1B, is a pivotal integrator of information in dopaminoceptive neurons, regulating the response to neuroleptics, psychotomimetics, and drugs of abuse, and affecting striatal function and plasticity. Des...

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Detalhes bibliográficos
Main Authors: Meyer-Lindenberg, Andreas, Straub, Richard E., Lipska, Barbara K., Verchinski, Beth A., Goldberg, Terry, Callicott, Joseph H., Egan, Michael F., Huffaker, Stephen S., Mattay, Venkata S., Kolachana, Bhaskar, Kleinman, Joel E., Weinberger, Daniel R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1784004/
https://ncbi.nlm.nih.gov/pubmed/17290303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30413
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