Interferon-α disables dendritic cell precursors: dendritic cells derived from interferon-α-treated monocytes are defective in maturation and T-cell stimulation

Dendritic cells (DC) can be derived from monocytes in vitro by culture with granulocyte–macrophage colony-stimulating factor (GM-CSF) and interleukin-4 (IL-4). It is unknown whether this regimen reflects DC differentiation from blood precursors under physiological conditions. Induction of DC develop...

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Bibliographic Details
Main Authors: Dauer, Marc, Pohl, Katrin, Obermaier, Bianca, Meskendahl, Tobias, Röbe, Julian, Schnurr, Max, Endres, Stefan, Eigler, Andreas
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2003
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783028/
https://ncbi.nlm.nih.gov/pubmed/12941139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2003.01702.x
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