Calcium-sensing mechanism in TRPC5 channels contributing to retardation of neurite outgrowth

The calcium- and sodium-permeable transient receptor potential channel TRPC5 has an inhibitory role in neuronal outgrowth but the mechanisms governing its activity are poorly understood. Here we propose a mechanism involving the neuronal calcium sensor-1 (NCS-1) protein. Inhibitory mutants of TRPC5...

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Main Authors: Hui, Hui, McHugh, Damian, Hannan, Meredith, Zeng, Fanning, Xu, Shang-Zhong, Khan, Saeed-ul-Hassan, Levenson, Robert, Beech, David J, Weiss, Jamie L
Formáid: Artigo
Teanga:Inglês
Foilsithe: Blackwell Science Inc 2006
Ábhair:
Molecular and Genomic Physiology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779652/
https://ncbi.nlm.nih.gov/pubmed/16469785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.102889
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