CREB/PKA sensitive signalling pathways activate and maintain expression levels of the hepatitis B virus pre-S2/S promoter

Background and aims: CREB (cAMP response element binding protein) transcription factors are key regulators of homeostatic functions in the liver, and CRE binding is increased in hepatic inflammation. During chronic hepatitis B virus (HBV) infection, mutations or deletions in the pre-S region are fre...

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Main Authors: Tacke, F, Liedtke, C, Bocklage, S, Manns, M P, Trautwein, C
格式: Artigo
語言:Inglês
出版: Copyright 2005 by Gut 2005
主題:
Hepatitis
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774645/
https://ncbi.nlm.nih.gov/pubmed/15871998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2005.065086
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