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Impaired CD95 expression predisposes for recurrence in curatively resected colon carcinoma: clinical evidence for immunoselection and CD95L mediated control of minimal residual disease

Background: Loss of CD95 expression in tumour cells occurs frequently in colon carcinoma and may be associated with disease progression. On the other hand, neo-expression of CD95L in tumour cells may contribute to immune evasion. Aims: We aimed at further exploring the functional role and prognostic...

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Autori principali: Sträter, J, Hinz, U, Hasel, C, Bhanot, U, Mechtersheimer, G, Lehnert, T, Möller, P
Natura: Artigo
Lingua:Inglês
Pubblicazione: Copyright 2005 by Gut 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774512/
https://ncbi.nlm.nih.gov/pubmed/15831912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2004.052696
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